An mRNA vaccine encoding Chikungunya virus E2-E1 protein elicits robust neutralizing antibody responses and CTL immune responses

Arthropod-borne chikungunya virus (CHIKV) infection can cause a debilitating arthritic disease in human. However, there are no specific antiviral drugs and effective licensed vaccines against CHIKV available for clinical use. Here, we developed an mRNA-lipid nanoparticle (mRNA-LNP) vaccine expressin...

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Detalles Bibliográficos
Autores principales: Ge, Ningning, Sun, Jin, Liu, Zhihua, Shu, Jiayi, Yan, Huimin, Kou, Zhihua, Wei, Yu, Jin, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170975/
https://www.ncbi.nlm.nih.gov/pubmed/35527225
http://dx.doi.org/10.1016/j.virs.2022.01.032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170975/
https://www.ncbi.nlm.nih.gov/pubmed/35527225
http://dx.doi.org/10.1016/j.virs.2022.01.032

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