Role of a conserved ion-binding site tyrosine in ion selectivity of the Na(+)/K(+) pump

The essential transmembrane Na(+) and K(+) gradients in animal cells are established by the Na(+)/K(+) pump, a P-type ATPase that exports three Na(+) and imports two K(+) per ATP hydrolyzed. The mechanism by which the Na(+)/K(+) pump distinguishes between Na(+) and K(+) at the two membrane sides is...

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Detalles Bibliográficos
Autores principales: Spontarelli, Kerri, Infield, Daniel T., Nielsen, Hang N., Holm, Rikke, Young, Victoria C., Galpin, Jason D., Ahern, Christopher A., Vilsen, Bente, Artigas, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171065/
https://www.ncbi.nlm.nih.gov/pubmed/35657726
http://dx.doi.org/10.1085/jgp.202113039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171065/
https://www.ncbi.nlm.nih.gov/pubmed/35657726
http://dx.doi.org/10.1085/jgp.202113039

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