A High Throughput Cell-Based Screen Assay for LINE-1 ORF1p Expression Inhibitors Using the In-Cell Western Technique

Long interspersed nuclear element 1 (LINE-1) is a dominant autonomous retrotransposon in human genomes which plays a role in affecting the structure and function of somatic genomes, resulting in human disorders including genetic disease and cancer. LINE-1 encoded ORF1p protein which possesses RNA-bi...

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Detalles Bibliográficos
Autores principales: Kou, Yanni, Wang, Shujie, Ma, Yanjie, Zhang, Ning, Zhang, Zixiong, Liu, Qian, Mao, Yang, Zhou, Rui, Yi, Dongrong, Ma, Ling, Zhang, Yongxin, Li, Quanjie, Wang, Jing, Wang, Jinhui, Zhou, Xile, He, Chunnian, Ding, Jiwei, Cen, Shan, Li, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171067/
https://www.ncbi.nlm.nih.gov/pubmed/35685648
http://dx.doi.org/10.3389/fphar.2022.881938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171067/
https://www.ncbi.nlm.nih.gov/pubmed/35685648
http://dx.doi.org/10.3389/fphar.2022.881938

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