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Lycorine Inhibits Hypertrophic Scar Formation by Inducing ROS-Mediated Apoptosis

Background: Hypertrophic scar (HS) is a fibrotic cutaneous disease with few effective therapies. Lycorine is a drug with pro-apoptotic ability and anti-fibrosis potential. This study aimed to test whether lycorine could trigger the apoptosis of hypertrophic scar fibroblasts (HSFs) to inhibit HS form...

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Detalles Bibliográficos
Autores principales: Dong, Yunxian, Lv, Dongming, Zhao, Zirui, Xu, Zhongye, Hu, Zhicheng, Tang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171077/
https://www.ncbi.nlm.nih.gov/pubmed/35685086
http://dx.doi.org/10.3389/fbioe.2022.892015