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Inhibitory Effect of Mitoxantrone on Collagen Synthesis in Dermal Fibroblasts

BACKGROUND: Fibroblasts produce collagen molecules that support the structure of the skin. The decrease and hypersynthesis of collagen causes skin problems such as skin atrophy, wrinkles and scars. OBJECTIVE: The purpose of this study is to investigate the mechanism of mitoxantrone on collagen synth...

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Detalles Bibliográficos
Autores principales: Kim, Kyung-Il, Kwon, Chang-Il, Lee, Jeung-Hoon, Kim, Chang-Deok, Yoon, Tae-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171176/
https://www.ncbi.nlm.nih.gov/pubmed/35721328
http://dx.doi.org/10.5021/ad.2022.34.3.206