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hnRNPL-activated circANKRD42 back-splicing and circANKRD42-mediated crosstalk of mechanical stiffness and biochemical signal in lung fibrosis

Increasing circular RNAs (circRNAs) are involved in the progression of idiopathic pulmonary fibrosis (IPF). However, circRNA biogenesis and circRNA-mediated crosstalk between mechanical stiffness and biochemical signals in IPF remain obscure. In this study, a novel circRNA-ankyrin repeat domain 42 (...

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Detalles Bibliográficos
Autores principales: Xu, Pan, Zhang, Jinjin, Wang, Meirong, Liu, Bo, Li, Rongrong, Li, Hongbo, Zhai, Nailiang, Liu, Weili, Lv, Changjun, Song, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171245/
https://www.ncbi.nlm.nih.gov/pubmed/35278674
http://dx.doi.org/10.1016/j.ymthe.2022.01.045