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Early empiric anti-Mycobacterium tuberculosis therapy for sepsis in sub-Saharan Africa: a protocol of a randomised clinical trial

INTRODUCTION: Sub-Saharan Africa shoulders the highest burden of global sepsis and associated mortality. In high HIV and tuberculosis (TB) prevalent settings such as sub-Saharan Africa, TB is the leading cause of sepsis. However, anti-TB therapy is often delayed and may not achieve adequate blood co...

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Detalles Bibliográficos
Autores principales: Said, Bibie, Nuwagira, Edwin, Liyoyo, Alphonce, Arinaitwe, Rinah, Gitige, Catherine, Mushagara, Rhina, Buzaare, Peter, Chongolo, Anna, Jjunju, Samuel, Twesigye, Precious, Boulware, David R, Conaway, Mark, Null, Megan, Thomas, Tania A, Heysell, Scott K, Moore, Christopher C, Muzoora, Conrad, Mpagama, Stellah G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171283/
https://www.ncbi.nlm.nih.gov/pubmed/35667721
http://dx.doi.org/10.1136/bmjopen-2022-061953