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Anti-TNF therapy for inflammatory bowel disease in patients with neurodegenerative Niemann-Pick disease Type C

Background:  Blockade of tumour necrosis factor (anti-TNF) is effective in patients with Crohn’s Disease but has been associated with infection risk and neurological complications such as demyelination. Niemann-Pick disease Type C1 (NPC1) is a lysosomal storage disorder presenting in childhood with...

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Detalles Bibliográficos
Autores principales: Williams, Isabelle, Pandey, Sumeet, Haller, Wolfram, Huynh, Hien Quoc, Chan, Alicia, Düeker, Gesche, Bettels, Ruth, Peyrin-Biroulet, Laurent, Dike, Chinenye R., DeGeeter, Catherine, Smith, David, Al Eisa, Nada, Platt, Nick, Marquardt, Thorsten, Schwerd, Tobias, Platt, Frances M., Uhlig, Holm H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171292/
https://www.ncbi.nlm.nih.gov/pubmed/35694196
http://dx.doi.org/10.12688/wellcomeopenres.16986.1