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Plasmodium falciparum Drug Resistance Genes pfmdr1 and pfcrt In Vivo Co-Expression During Artemether-Lumefantrine Therapy

Background: Artemisinin-based combination therapies (ACTs) are the global mainstay treatment of uncomplicated Plasmodium falciparum infections. PfMDR1 and PfCRT are two transmembrane transporters, associated with sensitivity to several antimalarials, found in the parasite food vacuole. Herein, we ex...

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Detalles Bibliográficos
Autores principales: Silva, M., Malmberg, M., Otienoburu, S. D., Björkman, A., Ngasala, B., Mårtensson, A., Gil, J. P., Veiga, M. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171324/
https://www.ncbi.nlm.nih.gov/pubmed/35685627
http://dx.doi.org/10.3389/fphar.2022.868723