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Brap regulates liver morphology and hepatocyte turnover via modulation of the Hippo pathway

Regulation of hepatocyte proliferation and liver morphology is of critical importance to tissue and whole-body homeostasis. However, the molecular mechanisms that underlie this complex process are incompletely understood. Here, we describe a role for the ubiquitin ligase BRCA1-associated protein (BR...

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Detalles Bibliográficos
Autores principales: Priest, Christina, Nagari, Rohith T., Bideyan, Lara, Lee, Stephen D., Nguyen, Alexander, Xiao, Xu, Tontonoz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171358/
https://www.ncbi.nlm.nih.gov/pubmed/35476518
http://dx.doi.org/10.1073/pnas.2201859119