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Catalpol Attenuates Pulmonary Fibrosis by Inhibiting Ang II/AT(1) and TGF-β/Smad-Mediated Epithelial Mesenchymal Transition

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive and devastating chronic lung condition affecting over 3 million people worldwide with a high mortality rate and there are no effective drugs. Angiotensin II (Ang II), as a major effector peptide of the renin angiotensin aldosterone sys...

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Detalles Bibliográficos
Autores principales: Yu, Qun, Zhu, Dewei, Zou, Yang, Wang, Kai, Rao, Peili, Shen, Yunhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171363/
https://www.ncbi.nlm.nih.gov/pubmed/35685407
http://dx.doi.org/10.3389/fmed.2022.878601