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An integrated model for Gpr124 function in Wnt7a/b signaling among vertebrates

Within the central nervous system, Wnt7a/b are unambiguously discriminated from other Wnt ligands by an endothelial receptor complex made of the glycosylphosphatidylinositol (GPI)-anchored Reck and the adhesion G protein-coupled receptor (GPCR) Gpr124. Reck is a Wnt7a/b-specific receptor, while Gpr1...

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Detalles Bibliográficos
Autores principales: America, Michelle, Bostaille, Naguissa, Eubelen, Marie, Martin, Maud, Stainier, Didier Y.R., Vanhollebeke, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171404/
https://www.ncbi.nlm.nih.gov/pubmed/35649360
http://dx.doi.org/10.1016/j.celrep.2022.110902