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Mechanisms of DNA damage‐mediated neurotoxicity in neurodegenerative disease
Neurons are highly susceptible to DNA damage accumulation due to their large energy requirements, elevated transcriptional activity, and long lifespan. While newer research has shown that DNA breaks and mutations may facilitate neuron diversity during development and neuronal function throughout lif...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171412/ https://www.ncbi.nlm.nih.gov/pubmed/35499251 http://dx.doi.org/10.15252/embr.202154217 |