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Tissue-Level Regeneration and Remodeling Dynamics are Driven by Mechanical Stimuli in the Microenvironment in a Post-Bridging Loaded Femur Defect Healing Model in Mice

Bone healing and remodeling are mechanically driven processes. While the generalized response to mechanical stimulation in bone is well-understood, much less is known about the mechanobiology-regulating tissue-scale bone formation and resorption during the reparative and remodeling phases of fractur...

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Detalles Bibliográficos
Autores principales: Paul, Graeme R., Vallaster, Paul, Rüegg, Michelle, Scheuren, Ariane C., Tourolle, Duncan C., Kuhn, Gisela A., Wehrle, Esther, Müller, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171432/
https://www.ncbi.nlm.nih.gov/pubmed/35686050
http://dx.doi.org/10.3389/fcell.2022.856204