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Tissue-Level Regeneration and Remodeling Dynamics are Driven by Mechanical Stimuli in the Microenvironment in a Post-Bridging Loaded Femur Defect Healing Model in Mice
Bone healing and remodeling are mechanically driven processes. While the generalized response to mechanical stimulation in bone is well-understood, much less is known about the mechanobiology-regulating tissue-scale bone formation and resorption during the reparative and remodeling phases of fractur...
Autores principales: | Paul, Graeme R., Vallaster, Paul, Rüegg, Michelle, Scheuren, Ariane C., Tourolle, Duncan C., Kuhn, Gisela A., Wehrle, Esther, Müller, Ralph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171432/ https://www.ncbi.nlm.nih.gov/pubmed/35686050 http://dx.doi.org/10.3389/fcell.2022.856204 |
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