A synthetic lethality screen reveals ING5 as a genetic dependency of catalytically dead Set1A/COMPASS in mouse embryonic stem cells

Embryonic stem cells (ESCs) are defined by their ability to self-renew and the potential to differentiate into all tissues of the developing organism. We previously demonstrated that deleting the catalytic SET domain of the Set1A/complex of proteins associated with SET1 histone methyltransferase (Se...

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Detalles Bibliográficos
Autores principales: Cenik, Bercin K., Sze, Christie C., Ryan, Caila A., Das, Siddhartha, Cao, Kaixiang, Douillet, Delphine, Rendleman, Emily J., Zha, Didi, Khan, Nabiha Haleema, Bartom, Elizabeth, Shilatifard, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171609/
https://www.ncbi.nlm.nih.gov/pubmed/35500115
http://dx.doi.org/10.1073/pnas.2118385119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171609/
https://www.ncbi.nlm.nih.gov/pubmed/35500115
http://dx.doi.org/10.1073/pnas.2118385119

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