Structural insights into Ras regulation by SIN1

Over the years it has been established that SIN1, a key component of mTORC2, could interact with Ras family small GTPases through its Ras-binding domain (RBD). The physical association of Ras and SIN1/mTORC2 could potentially affect both mTORC2 and Ras-ERK pathways. To decipher the precise molecular...

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Detalles Bibliográficos
Autores principales: Zheng, Yuyuan, Ding, Lei, Meng, Xianhui, Potter, Meg, Kearney, Alison L., Zhang, Jie, Sun, Jie, James, David E., Yang, Guang, Zhou, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171633/
https://www.ncbi.nlm.nih.gov/pubmed/35522713
http://dx.doi.org/10.1073/pnas.2119990119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171633/
https://www.ncbi.nlm.nih.gov/pubmed/35522713
http://dx.doi.org/10.1073/pnas.2119990119

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