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Autophagy induced by taurolidine protects against polymicrobial sepsis by promoting both host resistance and disease tolerance

Sepsis, septic shock, and their sequelae are the leading causes of death in intensive care units, with limited therapeutic options. Disease resistance and tolerance are two evolutionarily conserved yet distinct defense strategies that protect the host against microbial infection. Here, we report tha...

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Detalles Bibliográficos
Autores principales: Huang, Jie, Ita, Michael, Zhou, Huiting, Zhao, He, Hassan, Fara, Bai, Zhenjiang, O’Leary, D. Peter, Li, Yiping, Redmond, H. Paul, Wang, Jiang Huai, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171638/
https://www.ncbi.nlm.nih.gov/pubmed/35512102
http://dx.doi.org/10.1073/pnas.2121244119