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Autophagy induced by taurolidine protects against polymicrobial sepsis by promoting both host resistance and disease tolerance
Sepsis, septic shock, and their sequelae are the leading causes of death in intensive care units, with limited therapeutic options. Disease resistance and tolerance are two evolutionarily conserved yet distinct defense strategies that protect the host against microbial infection. Here, we report tha...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171638/ https://www.ncbi.nlm.nih.gov/pubmed/35512102 http://dx.doi.org/10.1073/pnas.2121244119 |