The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation

Argyrins are a family of naturally produced octapeptides that display promising antimicrobial activity against Pseudomonas aeruginosa. Argyrin B (ArgB) has been shown to interact with an elongated form of the translation elongation factor G (EF-G), leading to the suggestion that argyrins inhibit pro...

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Detalles Bibliográficos
Autores principales: Wieland, Maximiliane, Holm, Mikael, Rundlet, Emily J., Morici, Martino, Koller, Timm O., Maviza, Tinashe P., Pogorevc, Domen, Osterman, Ilya A., Müller, Rolf, Blanchard, Scott C., Wilson, Daniel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171646/
https://www.ncbi.nlm.nih.gov/pubmed/35500116
http://dx.doi.org/10.1073/pnas.2114214119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171646/
https://www.ncbi.nlm.nih.gov/pubmed/35500116
http://dx.doi.org/10.1073/pnas.2114214119

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