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Single-cell–resolution map of human retinal pigment epithelium helps discover subpopulations with differential disease sensitivity

Regional phenotypic and functional differences in the retinal pigment epithelium (RPE) monolayer have been suggested to account for regional susceptibility in ocular diseases such as age-related macular degeneration (AMD), late-onset retinal degeneration (L-ORD), and choroideremia (CHM). However, a...

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Detalles Bibliográficos
Autores principales: Ortolan, Davide, Sharma, Ruchi, Volkov, Andrei, Maminishkis, Arvydas, Hotaling, Nathan A., Huryn, Laryssa A., Cukras, Catherine, Di Marco, Stefano, Bisti, Silvia, Bharti, Kapil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171647/
https://www.ncbi.nlm.nih.gov/pubmed/35522714
http://dx.doi.org/10.1073/pnas.2117553119