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Neutrophils impose strong immune pressure against PfEMP1 variants implicated in cerebral malaria

Plasmodium falciparum, the deadliest form of human malaria, remains one of the major threats to human health in endemic regions. Its virulence is attributed to its ability to modify infected red blood cells (iRBC) to adhere to endothelial receptors by placing variable antigens known as PfEMP1 on the...

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Detalles Bibliográficos
Autores principales: Zelter, Tamir, Strahilevitz, Jacob, Simantov, Karina, Yajuk, Olga, Adams, Yvonne, Ramstedt Jensen, Anja, Dzikowski, Ron, Granot, Zvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171683/
https://www.ncbi.nlm.nih.gov/pubmed/35417070
http://dx.doi.org/10.15252/embr.202153641