Maladaptation after a virus host switch leads to increased activation of the pro-inflammatory NF-κB pathway

Myxoma virus (MYXV) causes localized cutaneous fibromas in its natural hosts, tapeti and brush rabbits; however, in the European rabbit, MYXV causes the lethal disease myxomatosis. Currently, the molecular mechanisms underlying this increased virulence after cross-species transmission are poorly und...

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Detalles Bibliográficos
Autores principales: Yu, Huibin, Peng, Chen, Zhang, Chi, Stoian, Ana M. M., Tazi, Loubna, Brennan, Greg, Rothenburg, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171774/
https://www.ncbi.nlm.nih.gov/pubmed/35549551
http://dx.doi.org/10.1073/pnas.2115354119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171774/
https://www.ncbi.nlm.nih.gov/pubmed/35549551
http://dx.doi.org/10.1073/pnas.2115354119

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