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Maladaptation after a virus host switch leads to increased activation of the pro-inflammatory NF-κB pathway
Myxoma virus (MYXV) causes localized cutaneous fibromas in its natural hosts, tapeti and brush rabbits; however, in the European rabbit, MYXV causes the lethal disease myxomatosis. Currently, the molecular mechanisms underlying this increased virulence after cross-species transmission are poorly und...
Autores principales: | Yu, Huibin, Peng, Chen, Zhang, Chi, Stoian, Ana M. M., Tazi, Loubna, Brennan, Greg, Rothenburg, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171774/ https://www.ncbi.nlm.nih.gov/pubmed/35549551 http://dx.doi.org/10.1073/pnas.2115354119 |
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