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Competing interactions give rise to two-state behavior and switch-like transitions in charge-rich intrinsically disordered proteins
The most commonly occurring intrinsically disordered proteins (IDPs) are polyampholytes, which are defined by the duality of low net charge per residue and high fractions of charged residues. Recent experiments have uncovered nuances regarding sequence–ensemble relationships of model polyampholytic...
Autores principales: | Zeng, Xiangze, Ruff, Kiersten M., Pappu, Rohit V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171777/ https://www.ncbi.nlm.nih.gov/pubmed/35512095 http://dx.doi.org/10.1073/pnas.2200559119 |
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