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Transsynaptic cerebellin 4–neogenin 1 signaling mediates LTP in the mouse dentate gyrus
Five decades ago, long-term potentiation (LTP) of synaptic transmission was discovered at entorhinal cortex→dentate gyrus (EC→DG) synapses, but the molecular determinants of EC→DG LTP remain largely unknown. Here, we show that the presynaptic neurexin–ligand cerebellin-4 (Cbln4) is highly expressed...
Autores principales: | Liakath-Ali, Kif, Polepalli, Jai S., Lee, Sung-Jin, Cloutier, Jean-Francois, Südhof, Thomas C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171784/ https://www.ncbi.nlm.nih.gov/pubmed/35544694 http://dx.doi.org/10.1073/pnas.2123421119 |
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