Targeted ubiquitination of sensory neuron calcium channels reduces the development of neuropathic pain
Neuropathic pain caused by lesions to somatosensory neurons due to injury or disease is a widespread public health problem that is inadequately managed by small-molecule therapeutics due to incomplete pain relief and devastating side effects. Genetically encoded molecules capable of interrupting noc...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171802/ https://www.ncbi.nlm.nih.gov/pubmed/35561213 http://dx.doi.org/10.1073/pnas.2118129119 |