Cargando…

APOBEC3A regulates transcription from interferon-stimulated response elements

APOBEC3A (A3A) is a cytidine deaminase that inactivates a variety of viruses through introduction of lethal mutations to the viral genome. Additionally, A3A can suppress HIV-1 transcription in a deaminase-independent manner by binding to the long terminal repeat of proviral HIV-1. However, it is unk...

Descripción completa

Detalles Bibliográficos
Autores principales: Taura, Manabu, Frank, John A., Takahashi, Takehiro, Kong, Yong, Kudo, Eriko, Song, Eric, Tokuyama, Maria, Iwasaki, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171812/
https://www.ncbi.nlm.nih.gov/pubmed/35549556
http://dx.doi.org/10.1073/pnas.2011665119