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Genes and evolutionary fates of the amanitin biosynthesis pathway in poisonous mushrooms

The deadly toxin α-amanitin is a bicyclic octapeptide biosynthesized on ribosomes. A phylogenetically disjunct group of mushrooms in Agaricales (Amanita, Lepiota, and Galerina) synthesizes α-amanitin. This distribution of the toxin biosynthetic pathway is possibly related to the horizontal transfer...

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Detalles Bibliográficos
Autores principales: Luo, Hong, Hallen-Adams, Heather E., Lüli, Yunjiao, Sgambelluri, R. Michael, Li, Xuan, Smith, Miranda, Yang, Zhu L., Martin, Francis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171917/
https://www.ncbi.nlm.nih.gov/pubmed/35533275
http://dx.doi.org/10.1073/pnas.2201113119