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Psoralen alleviates radiation-induced bone injury by rescuing skeletal stem cell stemness through AKT-mediated upregulation of GSK-3β and NRF2

BACKGROUND: Repairing radiation-induced bone injuries remains a significant challenge in the clinic, and few effective medicines are currently available. Psoralen is a principal bioactive component of Cullen corylifolium (L.) Medik and has been reported to have antitumor, anti-inflammatory, and pro-...

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Detalles Bibliográficos
Autores principales: Yin, Bo-Feng, Li, Zhi-Ling, Yan, Zi-Qiao, Guo, Zheng, Liang, Jia-Wu, Wang, Qian, Zhao, Zhi-Dong, Li, Pei-Lin, Hao, Rui-Cong, Han, Meng-Yue, Li, Xiao-Tong, Mao, Ning, Ding, Li, Chen, Da-Fu, Gao, Yue, Zhu, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172007/
https://www.ncbi.nlm.nih.gov/pubmed/35672836
http://dx.doi.org/10.1186/s13287-022-02911-2