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Dexmedetomidine prolongs the duration of local anesthetics when used as an adjuvant through both perineural and systemic mechanisms: a prospective randomized double-blinded trial

BACKGROUND: To study the respective peripheral and systemic mechanisms of action of dexmedetomidine, as adjuvant to regional anesthesia, we compared dexmedetomidine added to ropivacaine for mid-forearm nerve blocks, to either systemic-only dexmedetomidine, and to a control with no dexmedetomidine. M...

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Detalles Bibliográficos
Autores principales: Bao, Nana, Shi, Kejian, Wu, YiQuan, He, Yuting, Chen, Zhengjie, Gao, Yuan, Xia, Yun, Papadimos, Thomas J., Wang, Quanguang, Zhou, Riyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172023/
https://www.ncbi.nlm.nih.gov/pubmed/35672660
http://dx.doi.org/10.1186/s12871-022-01716-3