Metformin counteracts stimulatory effects induced by insulin in primary breast cancer cells

BACKGROUND: Metabolic disorders are associated with increased incidence, aggressive phenotype and poor outcome of breast cancer (BC) patients. For instance, hyperinsulinemia is an independent risk factor for BC and the insulin/insulin receptor (IR) axis is involved in BC growth and metastasis. Of no...

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Detalles Bibliográficos
Autores principales: Scordamaglia, Domenica, Cirillo, Francesca, Talia, Marianna, Santolla, Maria Francesca, Rigiracciolo, Damiano Cosimo, Muglia, Lucia, Zicarelli, Azzurra, De Rosis, Salvatore, Giordano, Francesca, Miglietta, Anna Maria, De Francesco, Ernestina Marianna, Vella, Veronica, Belfiore, Antonino, Lappano, Rosamaria, Maggiolini, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172136/
https://www.ncbi.nlm.nih.gov/pubmed/35672854
http://dx.doi.org/10.1186/s12967-022-03463-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172136/
https://www.ncbi.nlm.nih.gov/pubmed/35672854
http://dx.doi.org/10.1186/s12967-022-03463-y

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