Covalent labeling of a chromatin reader domain using proximity-reactive cyclic peptides

Chemical probes for chromatin reader proteins are valuable tools for investigating epigenetic regulatory mechanisms and evaluating whether the target of interest holds therapeutic potential. Developing potent inhibitors for the plant homeodomain (PHD) family of methylation readers remains a difficul...

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Detalles Bibliográficos
Autores principales: Zhang, Meng Yao, Yang, Hyunjun, Ortiz, Gloria, Trnka, Michael J., Petronikolou, Nektaria, Burlingame, Alma L., DeGrado, William F., Fujimori, Danica Galonić
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172573/
https://www.ncbi.nlm.nih.gov/pubmed/35756531
http://dx.doi.org/10.1039/d2sc00555g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172573/
https://www.ncbi.nlm.nih.gov/pubmed/35756531
http://dx.doi.org/10.1039/d2sc00555g

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