Cargando…

Aminoflavone upregulates putative tumor suppressor miR-125b-2-3p to inhibit luminal A breast cancer stem cell-like properties

Metastatic breast cancer is incurable and often due to breast cancer stem cell (CSC)-mediated self-renewal. We previously determined that the aryl hydrocarbon receptor (AhR) agonist aminoflavone (AF) inhibits the expression of the CSC biomarker α6-integrin (ITGA6) to disrupt the formation of luminal...

Descripción completa

Detalles Bibliográficos
Autores principales: Mavingire, Nicole, Campbell, Petreena, Liu, Tiantian, Wooten, Jonathan, Khan, Salma, Chen, Xin, Matthews, Jason, Wang, Charles, Brantley, Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172653/
https://www.ncbi.nlm.nih.gov/pubmed/35694715
http://dx.doi.org/10.1093/pcmedi/pbac008