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Aminoflavone upregulates putative tumor suppressor miR-125b-2-3p to inhibit luminal A breast cancer stem cell-like properties

Metastatic breast cancer is incurable and often due to breast cancer stem cell (CSC)-mediated self-renewal. We previously determined that the aryl hydrocarbon receptor (AhR) agonist aminoflavone (AF) inhibits the expression of the CSC biomarker α6-integrin (ITGA6) to disrupt the formation of luminal...

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Detalles Bibliográficos
Autores principales:	Mavingire, Nicole, Campbell, Petreena, Liu, Tiantian, Wooten, Jonathan, Khan, Salma, Chen, Xin, Matthews, Jason, Wang, Charles, Brantley, Eileen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172653/ https://www.ncbi.nlm.nih.gov/pubmed/35694715 http://dx.doi.org/10.1093/pcmedi/pbac008

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