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Mitochondrial Diabetes is Associated with tRNA(Leu(UUR)) A3243G and ND6 T14502C Mutations

BACKGROUND: Mutations in mitochondrial DNA (mtDNA) are associated with type 2 diabetes mellitus (T2DM). In particular, m.A3243G is the most common T2DM-related mtDNA mutation in many families worldwide. However, the clinical features and pathophysiology of m.A3243G-induced T2DM are largely undefined...

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Detalles Bibliográficos
Autores principales: Ding, Yu, Zhang, Shunrong, Guo, Qinxian, Zheng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172734/
https://www.ncbi.nlm.nih.gov/pubmed/35685248
http://dx.doi.org/10.2147/DMSO.S363978