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Mitochondrial Diabetes is Associated with tRNA(Leu(UUR)) A3243G and ND6 T14502C Mutations
BACKGROUND: Mutations in mitochondrial DNA (mtDNA) are associated with type 2 diabetes mellitus (T2DM). In particular, m.A3243G is the most common T2DM-related mtDNA mutation in many families worldwide. However, the clinical features and pathophysiology of m.A3243G-induced T2DM are largely undefined...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172734/ https://www.ncbi.nlm.nih.gov/pubmed/35685248 http://dx.doi.org/10.2147/DMSO.S363978 |