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Mitochondrial Diabetes is Associated with tRNA(Leu(UUR)) A3243G and ND6 T14502C Mutations

BACKGROUND: Mutations in mitochondrial DNA (mtDNA) are associated with type 2 diabetes mellitus (T2DM). In particular, m.A3243G is the most common T2DM-related mtDNA mutation in many families worldwide. However, the clinical features and pathophysiology of m.A3243G-induced T2DM are largely undefined...

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Detalles Bibliográficos
Autores principales:	Ding, Yu, Zhang, Shunrong, Guo, Qinxian, Zheng, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172734/ https://www.ncbi.nlm.nih.gov/pubmed/35685248 http://dx.doi.org/10.2147/DMSO.S363978

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