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Chronic Hypoxia in Ovine Pregnancy Recapitulates Physiological and Molecular Markers of Preeclampsia in the Mother, Placenta, and Offspring

Preeclampsia continues to be a prevalent pregnancy complication and underlying mechanisms remain controversial. A common feature of preeclampsia is utero-placenta hypoxia. In contrast to the impact of hypoxia on the placenta and fetus, comparatively little is known about the maternal physiology. MET...

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Detalles Bibliográficos
Autores principales: Tong, Wen, Allison, Beth J., Brain, Kirsty L., Patey, Olga V., Niu, Youguo, Botting, Kimberley J., Ford, Sage G., Garrud, Tessa A., Wooding, Peter F.B., Shaw, Caroline J., Lyu, Qiang, Zhang, Lin, Ma, Jin, Cindrova-Davies, Tereza, Yung, Hong Wa, Burton, Graham J., Giussani, Dino A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172902/
https://www.ncbi.nlm.nih.gov/pubmed/35534925
http://dx.doi.org/10.1161/HYPERTENSIONAHA.122.19175