Investigating CRISPR/Cas9 gene drive for production of disease-preventing prion gene alleles

Prion diseases are a group of fatal neurodegenerative disorders that includes chronic wasting disease, which affects cervids and is highly transmissible. Given that chronic wasting disease prevalence exceeds 30% in some endemic areas of North America, and that eventual transmission to other mammalia...

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Detalles Bibliográficos
Autores principales: Castle, Andrew R., Wohlgemuth, Serene, Arce, Luis, Westaway, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173614/
https://www.ncbi.nlm.nih.gov/pubmed/35671288
http://dx.doi.org/10.1371/journal.pone.0269342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173614/
https://www.ncbi.nlm.nih.gov/pubmed/35671288
http://dx.doi.org/10.1371/journal.pone.0269342

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