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Investigating CRISPR/Cas9 gene drive for production of disease-preventing prion gene alleles

Prion diseases are a group of fatal neurodegenerative disorders that includes chronic wasting disease, which affects cervids and is highly transmissible. Given that chronic wasting disease prevalence exceeds 30% in some endemic areas of North America, and that eventual transmission to other mammalia...

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Detalles Bibliográficos
Autores principales:	Castle, Andrew R., Wohlgemuth, Serene, Arce, Luis, Westaway, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173614/ https://www.ncbi.nlm.nih.gov/pubmed/35671288 http://dx.doi.org/10.1371/journal.pone.0269342

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