Simultaneous determination of four cobalamins in rat plasma using online solid phase extraction coupled to high performance liquid chromatography-tandem mass spectrometry: Application to pentylenetetrazole-induced seizures in Sprague-Dawley rats

A high throughput and high sensitive online solid phase extraction coupled to high performance liquid chromatography-tandem mass spectrometry method was established and validated for simultaneous quantification of four cobalamins including OHCbl, CNCbl, AdoCbl and MeCbl in rat plasma. Analytes were...

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Detalles Bibliográficos
Autores principales: Jiang, Xiaomei, Wang, Yan, Liu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173623/
https://www.ncbi.nlm.nih.gov/pubmed/35671315
http://dx.doi.org/10.1371/journal.pone.0269645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173623/
https://www.ncbi.nlm.nih.gov/pubmed/35671315
http://dx.doi.org/10.1371/journal.pone.0269645

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