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A Nonconventional Archaeal Fluorinase Identified by In Silico Mining for Enhanced Fluorine Biocatalysis

[Image: see text] Fluorinases, the only enzymes known to catalyze the transfer of fluorine to an organic molecule, are essential catalysts for the biological synthesis of valuable organofluorines. However, the few fluorinases identified so far have low turnover rates that hamper biotechnological app...

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Detalles Bibliográficos
Autores principales: Pardo, Isabel, Bednar, David, Calero, Patricia, Volke, Daniel C., Damborský, Jiří, Nikel, Pablo I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173684/
https://www.ncbi.nlm.nih.gov/pubmed/35692250
http://dx.doi.org/10.1021/acscatal.2c01184