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Fast bacterial growth reduces antibiotic accumulation and efficacy

Phenotypic variations between individual microbial cells play a key role in the resistance of microbial pathogens to pharmacotherapies. Nevertheless, little is known about cell individuality in antibiotic accumulation. Here, we hypothesise that phenotypic diversification can be driven by fundamental...

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Detalles Bibliográficos
Autores principales: Łapińska, Urszula, Voliotis, Margaritis, Lee, Ka Kiu, Campey, Adrian, Stone, M Rhia L, Tuck, Brandon, Phetsang, Wanida, Zhang, Bing, Tsaneva-Atanasova, Krasimira, Blaskovich, Mark AT, Pagliara, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173744/
https://www.ncbi.nlm.nih.gov/pubmed/35670099
http://dx.doi.org/10.7554/eLife.74062