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NOS2 and S-nitrosothiol signaling induces DNA hypomethylation and LINE-1 retrotransposon expression

Inducible nitric oxide synthase (NOS2) produces high local concentrations of nitric oxide (NO), and its expression is associated with inflammation, cellular stress signals, and cellular transformation. Additionally, NOS2 expression results in aggressive cancer cell phenotypes and is correlated with...

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Detalles Bibliográficos
Autores principales: Switzer, Christopher H., Cho, Hyun-Ju, Eykyn, Thomas R., Lavender, Paul, Eaton, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173756/
https://www.ncbi.nlm.nih.gov/pubmed/35584114
http://dx.doi.org/10.1073/pnas.2200022119