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Impact of natural selection on global patterns of genetic variation and association with clinical phenotypes at genes involved in SARS-CoV-2 infection

Human genomic diversity has been shaped by both ancient and ongoing challenges from viruses. The current coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had a devastating impact on population health. However, genetic diversity a...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Verma, Anurag, Feng, Yuanqing, Melo, Marcelo C. R., McQuillan, Michael, Hansen, Matthew, Lucas, Anastasia, Park, Joseph, Ranciaro, Alessia, Thompson, Simon, Rubel, Meagan A., Campbell, Michael C., Beggs, William, Hirbo, Jibril, Wata Mpoloka, Sununguko, George Mokone, Gaonyadiwe, Nyambo, Thomas, Wolde Meskel, Dawit, Belay, Gurja, Fokunang, Charles, Njamnshi, Alfred K., Omar, Sabah A., Williams, Scott M., Rader, Daniel J., Ritchie, Marylyn D., de la Fuente-Nunez, Cesar, Sirugo, Giorgio, Tishkoff, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173769/
https://www.ncbi.nlm.nih.gov/pubmed/35580180
http://dx.doi.org/10.1073/pnas.2123000119