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MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells

Middle East respiratory syndrome coronavirus (MERS-CoV) emerged into humans in 2012, causing highly lethal respiratory disease. The severity of disease may be, in part, because MERS-CoV is adept at antagonizing early innate immune pathways—interferon (IFN) production and signaling, protein kinase R...

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Detalles Bibliográficos
Autores principales: Comar, Courtney E., Otter, Clayton J., Pfannenstiel, Jessica, Doerger, Ethan, Renner, David M., Tan, Li Hui, Perlman, Stanley, Cohen, Noam A., Fehr, Anthony R., Weiss, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173776/
https://www.ncbi.nlm.nih.gov/pubmed/35594398
http://dx.doi.org/10.1073/pnas.2123208119