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MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells
Middle East respiratory syndrome coronavirus (MERS-CoV) emerged into humans in 2012, causing highly lethal respiratory disease. The severity of disease may be, in part, because MERS-CoV is adept at antagonizing early innate immune pathways—interferon (IFN) production and signaling, protein kinase R...
Autores principales: | Comar, Courtney E., Otter, Clayton J., Pfannenstiel, Jessica, Doerger, Ethan, Renner, David M., Tan, Li Hui, Perlman, Stanley, Cohen, Noam A., Fehr, Anthony R., Weiss, Susan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173776/ https://www.ncbi.nlm.nih.gov/pubmed/35594398 http://dx.doi.org/10.1073/pnas.2123208119 |
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