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Visualization of mutagenic nucleotide processing by Escherichia coli MutT, a Nudix hydrolase
Escherichia coli MutT prevents mutations by hydrolyzing mutagenic 8-oxo-2'-deoxyguanosine 5'-triphosphate (8-oxo-dGTP) in the presence of Mg(2+) or Mn(2+) ions. MutT is one of the most studied enzymes in the nucleoside diphosphate-linked moiety X (Nudix) hydrolase superfamily, which is wid...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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National Academy of Sciences
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173781/ https://www.ncbi.nlm.nih.gov/pubmed/35594391 http://dx.doi.org/10.1073/pnas.2203118119 |