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Modified climbing fiber/Purkinje cell synaptic connectivity in the cerebellum of the neonatal phencyclidine model of schizophrenia

Environmental perturbations during the first years of life are a major factor in psychiatric diseases. Phencyclidine (PCP), a drug of abuse, has psychomimetic effects, and neonatal subchronic administration of PCP in rodents leads to long-term behavioral changes relevant for schizophrenia. The cereb...

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Detalles Bibliográficos
Autores principales: Veleanu, Maxime, Urrieta-Chávez, Beetsi, Sigoillot, Séverine M., Paul, Maëla A., Usardi, Alessia, Iyer, Keerthana, Delagrange, Marine, Doyle, Joseph P., Heintz, Nathaniel, Bécamel, Carine, Selimi, Fekrije
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173783/
https://www.ncbi.nlm.nih.gov/pubmed/35588456
http://dx.doi.org/10.1073/pnas.2122544119