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Ki-67 assessment of pancreatic neuroendocrine neoplasms: Systematic review and meta-analysis of manual vs. digital pathology scoring

Ki-67 assessment is a key step in the diagnosis of neuroendocrine neoplasms (NENs) from all anatomic locations. Several challenges exist related to quantifying the Ki-67 proliferation index due to lack of method standardization and inter-reader variability. The application of digital pathology coupl...

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Detalles Bibliográficos
Autores principales: Luchini, Claudio, Pantanowitz, Liron, Adsay, Volkan, Asa, Sylvia L., Antonini, Pietro, Girolami, Ilaria, Veronese, Nicola, Nottegar, Alessia, Cingarlini, Sara, Landoni, Luca, Brosens, Lodewijk A., Verschuur, Anna V., Mattiolo, Paola, Pea, Antonio, Mafficini, Andrea, Milella, Michele, Niazi, Muhammad K., Gurcan, Metin N., Eccher, Albino, Cree, Ian A., Scarpa, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174054/
https://www.ncbi.nlm.nih.gov/pubmed/35249100
http://dx.doi.org/10.1038/s41379-022-01055-1